State of the Art
نویسنده
چکیده
Introduction Genetics of Elastase In vitro Substrates of Elastase—Clues to in vivo Function? Regulation and Function of Elastase Inhibition by and Evasion of Antiproteases Elastase Release by Neutrophils Involvement of Elastase in Neutrophil Transvascular Emigration into the Interstitium Membrane-bound Elastase: Vectorial Migration of the Neutrophil? Cytotoxicity and Wound Healing Evidence for the Role of Elastase in ARDS in Humans Animal Models of Lung Injury and Leukocyte Elastase Studies of Protease Inhibitors and Experimental Lung Injury Studies with Elastase Knockout Mice Studies of Elastase Inhibitors in Human Lung Injury in Sepsis Conclusions and Unanswered Questions A balance between injury and benefit: a modulator of the inflammatory response?
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